Download Arteriovenous Hemofiltration: A Kidney Replacement Therapy by Peter Kramer PDF

By Peter Kramer

Discovery and Relative value of constant Arteriovenous HemofIltration Lee W. Henderson non-stop arteriovenous hemofiltration (CAVH) has visible a brisk upswing in acceptance in Europe on account that its advent by means of Dr. Kramer and co-workers from Gottingen, West Germany in 1977 [1]. within the usa, the strategy re ceived approval as a scientific software from the meals and Drug management in April 1982. This approval flowed, in no small degree, from the large expe rience mentioned from Europe and particularly West Germany [e. g., 2, 3]. studies of its medical application now have all started to seem within the usa [4]. removing of extra overall physique water utilizing artificial membranes in an extracor poreal circuit dates again to the paintings of Alwall and the factitious kidney that he designed which accredited usage of a hydrostatic strain gradient to moti vate water movement around the membrane [5]. Kolffs unique rotating drum with its unencased membrane required an osmotic driver [6]. Hemofiltration, using the filtration procedure to take away uremic solutes with the bogus kidney, in analogy with the glomerulus, used to be mentioned in 1967 [7]. This was once made attainable by way of the supply of man-made membranes with a ways better hydraulic permeability (approximately 10 instances better) than conventionally used cellulosic hemodialysis membrane. particular functions of those "high flux" membranes to the elimination basically of extra overall physique water presently thereafter [8].

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